When I log into CIP I get a 500.19 error regarding permissions to the web.config file as shown in the screen capture below.
This HTTP error (500.19) may also happen when the tree containing the CIP application (for 17.4 this is C:\Cadence\CIP-E) is shared or permissions have changed after creation.
Verify the C:\Cadence\CIP-E folder and sub-folders have a group permission added to allow read/write/execute permission for the group “IIS_IUSRS”. This allows the IIS system to access the CIP application. Permission should be added to the Cadence folder as well as sub-folders.